Bioprocessing LIMS

A LIMS configured for biopharmaceutical manufacturing — upstream and downstream process sampling, in-process controls, and bioanalytical testing, all under 21 CFR Part 11.

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The Basics

What a Bioprocessing LIMS Actually Does


A bioprocess doesn't produce a handful of QC samples at the end — it generates a stream of them, all the way through. Every fermentation and cell-culture stage upstream, every purification step downstream, and every in-process control in between produces samples that have to be pulled on time, tested, and checked against limits before the process moves on. A bioprocessing LIMS is the system that keeps that stream under control.

It ties each sample to its process step and bioreactor stage, captures results and instrument data, gates the next step on in-process control limits, and assembles the whole batch's process history into a record you can trace and defend — with the audit trail and electronic signatures GMP demands.

Built for the Bioprocess Workflow

The capabilities a biologics process lab needs beyond routine QC.

Upstream

Fermentation & Cell Culture

Stage- and time-based sampling plans tied to bioreactors, with results tracked across the run.

Downstream

Purification Steps

Sampling and testing through each purification stage, with yield and purity tracked step to step.

Control

In-Process Controls

IPC limits that gate progression, so an out-of-limit result stops the next step instead of surfacing later.

Bioanalytical

Potency & Purity Assays

Bioanalytical, cell-based and immunoassay results captured with methods, controls and acceptance criteria.

Integrity

21 CFR Part 11

Electronic signatures, tamper-evident audit trail, and ALCOA+ controls across the whole batch history.

Instruments

Direct Data Capture

Instrument interfacing so analytical data flows into the record without manual transcription.

CORPEX

Bioprocessing on the CORPEX Platform


CORPEX brings bioprocess sampling, in-process control and bioanalytical testing together on one compliant core, alongside our BioLIMS for biochemical laboratories and StabLIMS for stability programs. For teams that also run SAP or another ERP, results and dispositions flow through our LIMS–SAP integration, so the bioprocess record and the business record stay in step.

See a Bioprocessing LIMS Built for GMP

Talk to a CORPEX specialist about configuring a LIMS for your upstream, downstream and bioanalytical workflows.

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Bioprocessing LIMS — Frequently Asked Questions

What is a bioprocessing LIMS?

A LIMS configured for biopharmaceutical manufacturing. It manages the sampling and testing around a bioprocess — upstream fermentation and cell culture, downstream purification, in-process controls, and release testing — linking process samples to results, specifications and the batch record with a full audit trail under 21 CFR Part 11 and GMP.

How is it different from a standard LIMS?

The core is the same, but a bioprocessing configuration adds sampling tied to process steps and bioreactor stages, in-process control limits that gate the next step, stage-based sampling plans, and trending across a batch's process history — handling the sample volume and timing of a live bioprocess rather than one-off QC samples.

Does it support 21 CFR Part 11 and GMP?

Yes. It provides electronic signatures, a tamper-evident audit trail, and ALCOA+ data-integrity controls compliant with FDA 21 CFR Part 11, with validation (IQ/OQ/PQ) support as part of implementation.

Can it handle bioanalytical testing?

Yes. Bioanalytical assays — potency, purity, cell-based and immunoassays — are captured with their methods, controls and acceptance criteria, results tied to the process sample and instrument data captured directly, keeping a defensible chain from raw data to the reported result.